Publications - Laboratoire Francois Michel Boisvert
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Publications récentes / Recent publications


Brunet MA, Lucier JF, Levesque M, Leblanc S, Jacques JF, Al-Saedi HRH, Guilloy N, Grenier F, Avino M, Fournier I, Salzet M, Ouangraoua A, Scott MS, Boisvert FM, Roucou X (2020).OpenProt 2021: deeper functional annotation of the coding potential of eukaryotic genomes.” Nucleic Acids Res. Nov 12:gkaa1036. doi: 10.1093/nar/gkaa1036

Roberts RF, Bayne AN, Goiran T, Lévesque D, Boisvert FM, Trempe JF, Fon EA. J (2020) “Proteomic Profiling of Mitochondrial-Derived Vesicles in Brain Reveals Enrichment of Respiratory Complex Sub-assemblies and Small TIM Chaperones.” Proteome Res. Nov 26. doi: 10.1021/acs.jproteome.0c00506

Masse MH, Battista MC, Wilcox ME, Pinto R, Marinoff N, D’Aragon F, St-Arnaud C, Mayette M, Leclair MA, Quiroz Martinez H, Grondin-Beaudoin B, Poulin Y, Carbonneau É, Seely AJE, Watpool I, Porteous R, Chassé M, Lebrasseur M, Lauzier F, Turgeon AF, Bellemare D, Mehta S, Charbonney E, Belley-Côté É, Botton É, Cohen D, Lamontagne F, Adhikari NKJ; OVATION-65 team members; Canadian Critical Care Trials Group (2020). “Optimal VAsopressor TitraTION in patients 65 years and older (OVATION-65): protocol and statistical analysis plan for a randomised clinical trial. BMJ Nov 14;10(11):e037947

Chesnel, F, Couturier, A, Alusse, A, Gagné, JP, Poirier, GG, Jean, D, Boisvert, FM, Hascoet, P, Paillard, L, Arlot-Bonnemains, Y, Le Goff, X (2020). “The prefoldin complex stabilizes the von Hippel-Lindau protein against aggregation and degradation.” PLoS Genetics, Nov 2, 16(11)

Lambert, E, Babeu, JP, Simoneau, J, Raisch, J, Lavergne, L, Lévesque, D, Jolibois, E, Avino, M, Scott, MS, Boudreau, F, Boisvert, FM (2020). “Human Hepatocyte Nuclear Factor 4-α Encodes Isoforms with Distinct Transcriptional Functions.” MCP, May 1, 19(5)

Dubois, ML, Meller, A, Samandi, S, Brunelle, M, Frion, J, Brunet, MA, Toupin, A, Beaudoin, MC, Jacques, JF, Lévesque, D, Scott, MS, Lavigne, P, Roucou, X, Boisvert, FM (2020). “UBB pseudogene 4 encodes functional ubiquitin variants.” Nat Comm, Mar 11; 1:1306

Babeu, J.-P., Wilson, S.D., Lambert, É., Lévesque, D., Boisvert, F. M. and Boudreau, F. (2019). Quantitative Proteomics Identifies DNA Repair as a Novel Biological Function for Hepatocyte Nuclear Facter 4a in Colorectal Cancer Cells.” Cancers (Basel) May 5;11(5).

Gonneaud, A., Turgeon, N., Jones, C., Couture, C., Lévesque, D., Boisvert, F. M., Boudreau, F. and Asselin, C. (2019). “HDAC1 and HDAC2 independently regulate common and specific intrinsic responses in murine enteroids.” Scientific Reports Mar 29; 9(1): 5363.

Gordon, M.H., Chauvin, A.,  Boisvert, F. M. and MacNaughton, W.K. (2019). “Proteolytic Processing of the Epithelial Adherens Junction Molecule E-Cadherin by Neutrophil Elastase Generates Short Peptides With Novel Would-Healing Bioactivity.” Cell Mol Gastroenterol Hepatol 7(2): 483-486.

Del Olmo, T., Lauzier, A., Normandin, C., Larcher, R., Lecours, M., Jean, D., Lessard, L., Steinberg, F., Boisvert, F. M. and Jean, S. (2019). “APEX2-mediated RAB proximity labeling identifies a role for RAB21 in clathrin-independent cargo sorting.” EMBO Reports Feb; 20(2).

Brunet, M.A., Brunelle, M., Lucier, J.-F., Delcourt, V., Lévesque, M., Grenier, F., Samandi, S., Leblanc, S., Aguilar, J.D., Dufour, P., Jacques, J.-F., Fournier, I., Ouangraoua, A., Scott, M.S., Boisvert, F.-M., Roucou, X. (2019). “OpenProt: a more comprehensive guide to explore eukaryotic coding potential and proteomes.” Nucleic Acids Research Jan 8; 47(D1)D403-410.

Drissi, R., Chauvin, A., McKenna, A., Lévesque, D., Blais-Brochu, S., Jean, D. and Boisvert, F. M. (2018). Destabilization of the MiniChromosome Maintenance (MCM) complex modulates the cellular response to DNA double strand breaks.” Cell Cycle 17(23):2593-2609.

Telekawa, C., Boisvert, F. M. and Bachand, F. (2018). “Proteomic profiling and functional characterization of post-translational modifications of the fission yeast RNA exosome.Nucleic Acids Research Nov 30; 46(21):11169-11183.

Chauvin, A., Wang, C.S., Geha, S., Garde-Granger, P., Mathieu, A.-A., Lacasse, V. and Boisvert, F. M. (2018). “The response to neoadjuvant chemoradiotherapy with 5-fluorouracil in locally advanced rectal cancer patients: a predictive proteomic signature.” Clinical Proteomics Apr 13; 15:16.

Chauvin, A. and Boisvert, F. M. (2018). “Proteomics Analysis of Colorectal Cancer Cells.” Methods Mol. Biol. 1765:155-166.

Asselin-Mullen, P., Chauvin, A., Dubois, M. L., Drissi, R., Levesque, D. and Boisvert, F. M. (2017). Protein interaction network of alternatively spliced NudCD1 isoforms.” Sci Rep 7(1): 12987.

Blain, J., Bedard, J., Thompson, M., Boisvert, F. M. and Boucher, M. J. (2017). “C-terminal deletion of NOTCH1 intracellular domain (N1ICD) increases its stability but does not amplify and recapitulate N1ICD-dependent signalling.” Sci Rep 7(1): 5034.

Gonneaud, A., Asselin, C., Boudreau, F. and Boisvert, F. M. (2017). “Phenotypic Analysis of Organoids by Proteomics.” Proteomics 17(20).

Gonneaud, A., Jones, C., Turgeon, N., Levesque, D., Asselin, C., Boudreau, F. and Boisvert, F. M.(2016). “A SILAC-Based Method for Quantitative Proteomic Analysis of Intestinal Organoids.” Sci Rep 6: 38195.

Landry-Voyer, A. M., S. Bilodeau, D. Bergeron, K. L. Dionne, S. A. Port, C. Rouleau, F. M. Boisvert, R. H. Kehlenbach and F. Bachand (2016). “Human PDCD2L is an export substrate of CRM1 that associates with 40S ribosomal subunit precursors.” Mol Cell Biol.

Mathieu, A. A., E. Ohl-Seguy, M. L. Dubois, D. Jean, C. Jones, F. Boudreau and F. M. Boisvert (2016). “Subcellular proteomics analysis of different stages of colorectal cancer cell lines.” Proteomics.

Thandapani, P., J. Song, V. Gandin, Y. Cai, S. G. Rouleau, J. M. Garant, F. M. Boisvert, Z. Yu, J. P. Perreault, I. Topisirovic and S. Richard (2015). “Aven recognition of RNA G-quadruplexes regulates translation of the mixed lineage leukemia protooncogenes.” Elife 4.

Gonneaud, A., N. Turgeon, F. M. Boisvert, F. Boudreau and C. Asselin (2015). “Loss of histone deacetylase Hdac1 disrupts metabolic processes in intestinal epithelial cells.” FEBS Lett 589(19 Pt B): 2776-83.

Drissi, R., Dubois, M.L., Douziech, M. and Boisvert, F.M. (2015) Quantitative proteomics reveals dynamic interactions of the MCM complex in the cellular response to etoposide induced DNA damage. Mol Cell Proteomics. in press

Marchand, B., Arsenault, D., Raymond-Fleury, A., Boisvert, F. and Boucher, M. (2015) Glycogen Synthase Kinase-3 (GSK3) inhibition induces pro-survival autophagic signals in human pancreatic cancer cells. J Biol Chem290, 5592-5605.

Drissi, R., Dubois, M.L. and Boisvert, F.M. (2013) Proteomics Methods for Subcellular Proteome Analysis. Febs J. 280, 5626-5634.

Vanderperre, B., Lucier, J.F., Bissonnette, C., Motard, J., Tremblay, G., Vanderperre, S., Wisztorski, M., Salzet, M., Boisvert, F.M. and Roucou, X. (2013) Direct detection of alternative open reading frames translation products in human significantly expands the proteome. PLoS One, 8, e70698.

Ahmad, Y., Boisvert, F.M., Lundberg, E., Uhlen, M. and Lamond, A.I. (2012) Systematic analysis of protein pools, isoforms, and modifications affecting turnover and subcellular localization. Mol Cell Proteomics, 11, M111 013680.

Boisvert, F.M., Ahmad, Y., Gierlinski, M., Charriere, F., Lamont, D., Scott, M., Barton, G. and Lamond, A.I. (2012) A quantitative spatial proteomics analysis of proteome turnover in human cells.Mol Cell Proteomics, 11, M111 011429.

Kliszczak, A.E., Rainey, M.D., Harhen, B., Boisvert, F.M. and Santocanale, C. (2011) DNA mediated chromatin pull-down for the study of chromatin replication. Sci Rep, 1, 95.

Moore, H.M., Bai, B., Boisvert, F.M., Latonen, L., Rantanen, V., Simpson, J.C., Pepperkok, R., Lamond, A.I. and Laiho, M. (2011) Quantitative proteomics and dynamic imaging of the nucleolus reveals distinct responses to UV and ionizing radiation. Mol Cell Proteomics. 10(10) M111.009241.

Dixon, M.J., Gray, A., Boisvert, F.M., Agacan, M., Morrice, N.A., Gourlay, R., Leslie, N.R., Downes, C.P. and Batty, I.H. (2011) A screen for novel phosphoinositide 3-kinase effector proteins. Mol Cell Proteomics, 10, M110 003178.

Scott, M.S., Boisvert, F.M., Lamond, A.I. and Barton, G.J. (2011) PNAC: a protein nucleolar association classifier. BMC Genomics12, 74.

Chamousset, D., De Wever, V., Moorhead, G.B., Chen, Y., Boisvert, F.M., Lamond, A.I. and Trinkle-Mulcahy, L. (2010) RRP1B targets PP1 to mammalian cell nucleoli and is associated with Pre-60S ribosomal subunits. Mol Biol Cell21, 4212-4226.

Boisvert, F.M. and Lamond, A.I. (2010) p53-Dependent subcellular proteome localization following DNA damage. Proteomics10, 4087-4097.

Scott, M.S., Boisvert, F.M., McDowall, M.D., Lamond, A.I. and Barton, G.J. (2010) Characterization and prediction of protein nucleolar localization sequences.Nucleic Acids Res38, 7388-7399.

Chamousset, D., Mamane, S., Boisvert, F.M. and Trinkle-Mulcahy, L. (2010) Efficient extraction of nucleolar proteins for interactome analyses. Proteomics10, 3045-3050.

Boisvert, F.M., Lam, Y.W., Lamont, D. and Lamond, A.I. (2010) A quantitative proteomics analysis of subcellular proteome localization and changes induced by DNA damage. Mol Cell Proteomics9, 457-470.

Ahmad, Y., Boisvert, F.M., Gregor, P., Cobley, A. and Lamond, A.I. (2009) NOPdb: Nucleolar Proteome Database–2008 update. Nucleic Acids Res37, D181-184.

Trinkle-Mulcahy, L., Boulon, S., Lam, Y.W., Urcia, R., Boisvert, F.M., Vandermoere, F., Morrice, N.A., Swift, S., Rothbauer, U., Leonhardt, H. and Lamond, A. (2008) Identifying specific protein interaction partners using quantitative mass spectrometry and bead proteomes. J Cell Biol183, 223-239.

Gonsalvez, G.B., Tian, L., Ospina, J.K., Boisvert, F.M., Lamond, A.I. and Matera, A.G. (2007) Two distinct arginine methyltransferases are required for biogenesis of Sm-class ribonucleoproteins. J Cell Biol178, 733-740.

Boisvert, F.M., Rhie, A., Richard, S. and Doherty, A.J. (2005) The GAR motif of 53BP1 is arginine methylated by PRMT1 and is necessary for 53BP1 DNA binding activity. Cell Cycle4, 1834-1841.

Boisvert, F.M., Hendzel, M.J., Masson, J.Y. and Richard, S. (2005) Methylation of MRE11 regulates its nuclear compartmentalization. Cell Cycle4, 981-989.

Boisvert, F.M., Dery, U., Masson, J.Y. and Richard, S. (2005) Arginine methylation of MRE11 by PRMT1 is required for DNA damage checkpoint control. Genes Dev, 19, 671-676.

Boisvert, F.M., Cote, J., Boulanger, M.C. and Richard, S. (2003) A proteomic analysis of arginine-methylated protein complexes. Mol Cell Proteomics2, 1319-1330.

Cote, J., Boisvert, F.M., Boulanger, M.C., Bedford, M.T. and Richard, S. (2003) Sam68 RNA binding protein is an in vivo substrate for protein arginine N-methyltransferase 1. Mol Biol Cell14, 274-287.

Boisvert, F.M., Cote, J., Boulanger, M.C., Cleroux, P., Bachand, F., Autexier, C. and Richard, S. (2002) Symmetrical dimethylarginine methylation is required for the localization of SMN in Cajal bodies and pre-mRNA splicing.J Cell Biol159, 957-969.

Vieyra, D., Loewith, R., Scott, M., Bonnefin, P., Boisvert, F.M., Cheema, P., Pastyryeva, S., Meijer, M., Johnston, R.N., Bazett-Jones, D.P., McMahon, S., Cole, M.D., Young, D. and Riabowol, K. (2002) Human ING1 proteins differentially regulate histone acetylation.J Biol Chem277, 29832-29839.

Bachand, F., Boisvert, F.M., Cote, J., Richard, S. and Autexier, C. (2002) The product of the survival of motor neuron (SMN) gene is a human telomerase-associated protein. Mol Biol Cell13, 3192-3202.

Scott, M., Bonnefin, P., Vieyra, D., Boisvert, F.M., Young, D., Bazett-Jones, D.P. and Riabowol, K. (2001) UV-induced binding of ING1 to PCNA regulates the induction of apoptosis. J Cell Sci114, 3455-3462.

Scott, M., Boisvert, F.M., Vieyra, D., Johnston, R.N., Bazett-Jones, D.P. and Riabowol, K. (2001)UV induces nucleolar translocation of ING1 through two distinct nucleolar targeting sequences.Nucleic Acids Res29, 2052-2058.

Cote, F., Boisvert, F.M., Grondin, B., Bazinet, M., Goodyer, C.G., Bazett-Jones, D.P. and Aubry, M. (2001) Alternative promoter usage and splicing of ZNF74 multifinger gene produce protein isoforms with a different repressor activity and nuclear partitioning. DNA Cell Biol, 20, 159-173.

Wheaton, K., Sampsel, K., Boisvert, F.M., Davy, A., Robbins, S. and Riabowol, K. (2001) Loss of functional caveolae during senescence of human fibroblasts. J Cell Physiol187, 226-235.

Boisvert, F.M., Kruhlak, M.J., Box, A.K., Hendzel, M.J. and Bazett-Jones, D.P. (2001) The transcription coactivator CBP is a dynamic component of the promyelocytic leukemia nuclear body. J Cell Biol152, 1099-1106.

Revues et chapitres de livre/Review Articles and Book Chapters

Boisvert, F.M., Hendzel, M.J. and Bazett-Jones, D.P. (2000) Promyelocytic leukemia (PML) nuclear bodies are protein structures that do not accumulate RNA. J Cell Biol148, 283-292.

Hendzel, M.J., Boisvert, F. and Bazett-Jones, D.P. (1999) Direct visualization of a protein nuclear architecture. Mol Biol Cell10, 2051-2062.

Chen, T., Boisvert, F.M., Bazett-Jones, D.P. and Richard, S. (1999) A role for the GSG domain in localizing Sam68 to novel nuclear structures in cancer cell lines. Mol Biol Cell10, 3015-3033.

Revues et chapitres de livre / Review Articles and Book Chapters

Chauvin, A. and Boisvert, F.-M. (2018) Clinical Proteomics in Colorectal Cancer, a Promising Tool for Improving Personalised Medecine. Proteomes. Dec 2; 6(4).

Gonneaud, A., Asselin, C., Boudreau, F. and Boisvert, F.-M. (2017) Phenotypic analysis of organoids by proteomics. Proteomics. Oct; 17(20).

Dubois, M.-L. and Boisvert, F.-M. (2016) The Dynamic Functions of the Nucleolus. Book Chapter in The Nucleus. Springer Editions.

Boisvert, F.-M. (2012) Chapter 1072: Nucleolus. Encyclopedia of Genetics, 2nd Edition. Elsevier.

Boisvert, F.-M., Ahmad, Y. and Lamond A.I. (2011) The Nucleolus. Chapter 20: The Dynamic Proteome of the Nucleolus. Springer Editions. Mark Olson Editor. 2.

Hutton, S., Westman, B.J., Boisvert, F.-M., van Koningsbruggen, S. and Lamond A.I. (2010) Protein Reviews, Chapter 12: The Nucleous.

Boulon, S., Westman, B.J., Hutten, S., Boisvert, F.M. and Lamond, A.I. (2010) The nucleolus under stress. Mol Cell40, 216-227.

Boisvert, F.M., van Koningsbruggen, S., Navascues, J. and Lamond, A.I. (2007) The multifunctional nucleolus. Nat Rev Mol Cell Biol8, 574-585.

Boisvert, F.M., Dery, U., Masson, J.Y. and Richard, S. (2005) [A new role for arginine methylation in DNA repair]Med Sci (Paris), 21, 579-581.

Boisvert, F.M., Chenard, C.A. and Richard, S. (2005) Protein interfaces in signaling regulated by arginine methylation. Sci STKE2005, re2.

Boisvert, F.M. and Richard, S. (2004) Arginine methylation regulates the cytokine response.Mol Cell15, 492-494.

Scott, M., Bonnefin, P., Vieyra, D., Boisvert, F.M., Young, D., Bazett-Jones, D.P. and Riabowol, K. (2001) UV-induced binding of ING1 to PCNA regulates the induction of apoptosis. J Cell Sci114, 3455-3462.